![]() ![]() developed a colorimetric determination of dexamethasone in tablets using UV-Vis spectrophotometry. One of them is by using a spectrophotometric approach. The development of dexamethasone analysis methods is continuing to find the alternative method that is low cost, effective, and sensitive. Several analytical methods have been used for detecting dexamethasone in herbal medicine, including high-performance liquid chromatography, infrared spectroscopy that combined with the partial least square (PLS), thin layer chromatography (TLC)-densitometry, and paper-based analytical device. Therefore, monitoring dexamethasone in herbal medicine is important. ![]() However, uncontrolled consumption of dexamethasone will cause some adverse effects such as vomiting, malaise, insomnia, anxiety until psychosis, aggravation of schizophrenia, and moon face. ĭexamethasone is a glucocorticoid that acts as a very potent and long-acting anti-inflammatory agent with the mechanism of action of reducing the production of inflammatory mediators such as suppressing the increase in neutrophils, reversing the increase in capillary permeability, and suppressing the immune response. One of the undeclared synthetic drugs in herbal medicine is dexamethasone. Since the market for herbal medicine is growing up continuously, there are reports that herbal medicine contains an undeclared synthetic drug to increase the therapeutic effect. ![]() To their definition, herbal medicine should not contain a synthetic chemical or medicinal isolation result. Herbal medicines are naturally occurring plant-derived substances used for treatment or medicinal purposes. Herbal medicine is still widely used as a drug or an alternative medicine to treat diseases. The UV-Vis spectrophotometry method is simple and effective for dexamethasone analysis in herbal medicine. The result showed six samples confirmed containing dexamethasone with levels ranging from 7.44 to 21.61 μg/mL and confirmed with HPLC data. The sixteen herbal medicine samples were analyzed to confirm the application of this method. Under optimized conditions, the performance of this system to analyze dexamethasone exhibited a good analytical response. ![]() To determine the content of dexamethasone in herbal medicine, a quantitative analytical method was developed with the reaction of the formation of a dexamethasone-hydroxylamine complex with fluoranil which was measured by UV-Vis spectrophotometry. One of them is dexamethasone which is added in herbal pain relief. Chemical drugs have been added to some of the traditional herbal medicine to enhance the therapeutic effect. ![]()
0 Comments
Leave a Reply. |
AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |